Many measures taken over the past decade have concentrated on enhancing urban sustainability at the level of built elements (building, building elements and materials, planning regulations on plot scale). However, the syntactical spatio-structural properties of the City as Living System still is poorly understood. It is expected that carrying capacity and ecological performance of UGI is highly dependent on the spatial and temporal coherence and continuity of new gray-green infrastructure networks. Therefore, it is crucial to develop transformation projects which help to establish or enhance these superordinate network structures to enhance performance characteristics of the UGI and raise awareness in society towards environmental aspects embedded in ongoing transformation processes. In a short-term perspective future mobility trends which in the city come along with megatrends like digitization and new forms of housing and work are of particular interest, since they might unfold powerful potential for urban reconstruction which can explicitly be activated for implementation of UGI. Reciprocally, it is expected that the presence of UGI will have a substantial impact on the use patterns/routines of the city and subsequently catalyze further reconstruction processes and promote new set-ups for urban projects (location, mix, contextual conditions) which need to be mirrored sufficiently in ongoing qualification processes of the networks to assure future connectivity, adaptability, and resilience.